Dieser Anti-ErbB2/Her2 (Pertuzumab Biosimilar) Antikörper ist ein Humanized Monoklonal Antikörper zur Detektion von ErbB2/Her2 (Pertuzumab Biosimilar) in FACS und in vivo. Geeignet für Human.
Produktnummer ABIN7200658
Kurzübersicht für Rekombinanter ErbB2/Her2 (Pertuzumab Biosimilar) Antikörper (ABIN7200658)
Target
ErbB2/Her2 (Pertuzumab Biosimilar)
Antikörpertyp
Recombinant Antibody
Reaktivität
Human
Wirt
Humanized
Klonalität
Monoklonal
Konjugat
Dieser ErbB2/Her2 (Pertuzumab Biosimilar) Antikörper ist unkonjugiert
Applikation
Flow Cytometry (FACS), In vivo Studies (in vivo)
Güteklasse
Research Grade
Verwendungszweck
Pertuzumab Biosimilar, Human HER2 Monoclonal Antibody
Spezifität
The monoclonal antibody pertuzumab biosimilar specifically binds to the human HER2/ErbB-2/c-neu.
Produktmerkmale
Pertuzumab, a humanized monoclonal antibody, inhibits HER dimerization and is used for the treatment of HER2-positive metastatic breast cancer, in combination with trastuzumab and docetaxel. By binding to HER2, Pertuzumab inhibits the dimerization of HER2 with other HER receptors, resulting in slowed tumor growth.
Aufreinigung
Protein A or G affinity column
Reinheit
>95 % by reducing SDS-PAGE
Sterilität
0.2 μm filtered
Endotoxin-Niveau
< 1 EU per 1 mg of the protein by the LAL method
Immunogen
The monoclonal antibody pertuzumab biosimilar was produced in the pertuzumab biosimilar CHO stable cell line.
Research Grade
Reaktivität: Human
Wirt: Mammalian Cells
Monoclonal
unconjugated
Recombinant Antibody
Applikationshinweise
ELISA, neutralization, functional assays such as bioanalytical PK and ADA assays, and those assays for studying biological pathways affected by pertuzumab.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
> 3 mg/mL
Buffer
PBS, pH 7.4, no stabilizers or preservatives.
Konservierungsmittel
Without preservative
Lagerung
4°C,-20 °C
Informationen zur Lagerung
12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.